Rena Papaspyrou was born in Athens in 1938.

1956-61 Attended the Athens School of Fine Arts
1963-67 Attended Ecole Nationale Supérieure des Beaux Arts, Paris
1993-2005 Professor at the Athens School of Fine Arts.
Director of the 3rd Painting Workshop
2006 Emeritus professor at the Athens School of Fine Arts.

Lives and works in Athens.